Synthesis of racemic cis and trans 2,4,5-tripyridylimidazolines
โ Scribed by Martin L. Larter; Mimi Phillips; Fernando Ortega; Gerardo Aguirre; Ratnasamy Somanathan; Patrick J. Walsh
- Book ID
- 104259469
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 232 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A method for synthesis of cis-end trans-polysubstituted 2,5-dihydronicotinonitri~es III from ~,N-disubstituted arylacetamidines I and ylidenemalononitriles II at room temperature in THF is reported.
## Abstract A method is described for the synthesis of the racemic [methylโd~3~] forms of the nicotine metabolites __cis__โ3โฒโhydroxycotinine and __trans__โ3โฒโhydroxycotinine. The key intermediate was [methylโd~3~]โNโmethylhydroxylamine, obtained from a selective hydrogenation of d~3~โnitroโmethane