## Abstract Two novel cannabinoid model compounds, (3__R__, 4__R__)‐Δ^1(6)^‐tetrahydrocannabinol‐5″‐oic acid **(22)** and 4″(__R__, __S__)‐methyl‐(3__R__, 4__R__)‐Δ^1(6)^‐tetrahydrocannabinol‐5″‐oic acid **(23)** were synthesized by acid‐catalyzed condensation of (+)‐__trans‐p__‐mentha‐2, 8‐dien‐l‐
✦ LIBER ✦
Synthesis of racemic and optically active Δ1- and Δ6-3,4-cis-tetrahydrocannabinols
✍ Scribed by D.B. Uliss; R.K. Razdan; H.C. Dalzell; G.R. Handrick
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 576 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4020
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## I I94 The synthesis was performed on a 10 g scale and (S)-a-methylserine had an enantiomeric purity of >99% as assessed by gas chromatographic enantiomeric analysis.