Synthesis of quinoxalineand isoquinoline-5,8-quinones
β Scribed by Yu. S. Tsizin; S. A. Chernyak
- Book ID
- 112331516
- Publisher
- Springer US
- Year
- 1975
- Tongue
- English
- Weight
- 92 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0009-3122
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π SIMILAR VOLUMES
## Abstract The title compound **3f** is a novel isolable 1,10βanthraquinone which is stabilized only by alkyl groups. Despite of the shielding of the __meso__ position **3f** reacts very fast with water and oxygen to give 3β__tert__βbutylβ1βhydroxyβ5,8βdimethylβ9,10βanthraquinone (**4f**).
A new and facile method for the preparation of isoquinolinequinone derivatives has been developed. Treatment of 2-acyl-1,4-naphthoquinones or 2-acyl-5,6-dimethyl-1,4-benzoquinones with enamines (or imines), followed by addition of aqueous NH 3 in MeOH afforded benz[g]isoquinoline-5,10-dione or isoqu