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Synthesis of quinoline thioethers as novel small molecule enhancers of monoclonal antibody production in mammalian cell culture

โœ Scribed by Shahid A. Kazi; Geoffrey F. Kelso; Simon Harris; Reinhard I. Boysen; Jamil Chowdhury; Milton Hearn


Book ID
108283407
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
551 KB
Volume
66
Category
Article
ISSN
0040-4020

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## Abstract Small molecule additives to cell culture media (e.g., sodium butyrate) that are capable of enhancing the expression of recombinant proteins have significant utility in the production and manufacture of therapeutic polypeptides. To identify novel small molecule enhancers (SMEs) of recomb