Application of the Chelate-Enolate Clais
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Kazmaier, Uli
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Article
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1997
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John Wiley and Sons
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English
⚖ 1000 KB
## Abstract Deprotonation of __N__‐protected amino acid allylic esters with LDA at −78°C and subsequent addition of a metal salt presumably results in the formation of a chelated metal enolate that undergoes Claisen rearrangement upon warming up to room temperature, giving rise to __γ,δ__‐unsaturat