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Synthesis of quaternary amino acids containing β,γ- as well as γ,δ-unsaturated side chains via chelate-enolate claisen rearrangement

✍ Scribed by Uli Kazmaier


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
214 KB
Volume
37
Category
Article
ISSN
0040-4039

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📜 SIMILAR VOLUMES


Application of the Chelate-Enolate Clais
✍ Kazmaier, Uli 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 1000 KB

## Abstract Deprotonation of __N__‐protected amino acid allylic esters with LDA at −78°C and subsequent addition of a metal salt presumably results in the formation of a chelated metal enolate that undergoes Claisen rearrangement upon warming up to room temperature, giving rise to __γ,δ__‐unsaturat