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Synthesis of pyrylium salts from trisubstituted 1,4-pentadiyn-3-ols with HClO4

โœ Scribed by Shin'ichi Nakatsuji; Kenichiro Nakashima; Kimiaki Yamamura; Shuzo Akiyama


Book ID
104233912
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
194 KB
Volume
25
Category
Article
ISSN
0040-4039

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Efficient synthesis of trisubstituted [1
โœ Yuan-Xiu Liao; Pei-Yu Kuo; Ding-Yah Yang ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 128 KB

Various trisubstituted [1]benzopyrano[4,3-b]pyrrol-4(1H)-one derivatives have been synthesized from 4-hydroxycoumarin with a 30-40% yield over six steps. The key step of the synthesis is a base-promoted intramolecular cyclization of enamines 5, followed by dehydration to generate the fused pyrrole r