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Synthesis of Protected syn 1,3-Diols by Intramolecular Conjugate Addition to Vinyl Sulfones.

✍ Scribed by Laurence Grimaud; Delphine Rotulo; Rafael Ros-Perez; Ludivine Guitry-Azam; Joelle Prunet


Publisher
John Wiley and Sons
Year
2003
Weight
131 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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Dipolar cycloaddition / Nitrile oxides / CΟͺO bond cleavage / Nitro alkenes An enantioselective synthesis of N-protected amino diols has Subsequent diastereo-and regioselective cycloaddition reactions to highly substituted 4,5-isoxazolines 5a-e, 8a, b been accomplished by employing a diastereoselect