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Synthesis of prostaglandins during anaphylaxis in guineapig lung

✍ Scribed by K.J. Barrett-Bee; I.F. Skidmore

Publisher
Elsevier Science
Year
1979
Weight
116 KB
Volume
2
Category
Article
ISSN
0161-4630

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Mouse myeloid leukemia cells (MI) were induced to differentiate into mature macrophages and granulocytes by various inducers. The differentiated M1 cells synthesized and released prostaglandins, whereas untreated M1 cells did not. When the cells were prelabelled with [ 14C]arachidonate, the major pr