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Synthesis of Precursors of Heterocyclic cis-β-Amino Alcohols by Intramolecular Amidoalkylation of 4-Hydroxyoxazolidin-2-ones.

✍ Scribed by N. B. Chernysheva; A. A. Bogolyubov; V. V. Murav'ev; V. V. Elkin; V. V. Semenov


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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A flexible and efficient synthesis of enantiomerically pure 4,5-substituted 2-oxazolidinonesimportant target molecules as precursors of pharmacologically active 2-oxazolidinones, β-amino alcohols, β-blockers and azasugar derivatives is described. As starting materials, the enantiopure storage forms