Synthesis and reactivity of cyanomethyl
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Samia M. Sayed; Mohamed A. Raslan; Mohamed A. Khalil; Kamal M. Dawood
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Article
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1999
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John Wiley and Sons
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English
โ 168 KB
๐ 1 views
The novel and versatile cyanomethyl 2amino-4-methylthiazolyl ketone (5) was prepared by treatment of bromomethyl 2-amino-4-methyl thiazolyl ketone (4) with potassium cyanide. Reaction of 5 with heterocyclic diazonium salts 6a,b and 10 afforded the corresponding hydrazones 7a,b and 11, respectively.