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Synthesis of Polysubstituted Pyrroles from Nitroso-Diels—Alder Cycloadducts.

✍ Scribed by Geraldine Calvet; Nicolas Blanchard; Cyrille Kouklovsky


Publisher
John Wiley and Sons
Year
2006
Weight
42 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract New spirocyclic heterocycles **8, 16, 19/20, 25, 27**, and **30** derived from pyrimido[4,5‐__b__][1,4]diazepin]‐8′(9′__H__)‐one were synthesised by a tandem nitroso‐ene/__Diels–Alder__ reaction of 4‐(alkenoylamino)‐5‐nitrosopyrimides. The crystal structure of **16** was established by