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SYNTHESIS OF POLYFUSED HETEROCYCLIC SYSTEMS DERIVED FROM FUNCTIONALLY SUBSTITUTED THIENO(2,3-b)THIOPHENE MOEITY

โœ Scribed by El-shafei, A. K.; El-saghier, A. M. M.; Sultan, A.; Soliman, A. M.


Book ID
111680888
Publisher
Taylor and Francis Group
Year
1992
Tongue
English
Weight
345 KB
Volume
72
Category
Article
ISSN
1042-6507

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A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonamide 6,6-dioxides. These cyclic vinyl sulfones readily underwent add