✦ LIBER ✦

Synthesis of polyfunctionally substituted pyridazines

✍ Scribed by Ghozlan, Said Ahmed Soliman ;Mohamed, Mona Hassan ;Fakhr, Yehia ;Elnagdi, Mohamed Hilmy

Book ID: 102367095
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 322 KB
Volume: 1990
Category: Article
ISSN: 0947-3440
DOI: 10.1002/jlac.199019900153

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The pyridazines 3, 4, 5, and 7 were obtained by reaction of the hydrazone derivatives 2 with several reagents. By treatment of 5 with acetic acid/hydrochloric acid, the pyrazolo[4,3‐c]‐pyridazine 6 was formed. The pyrido‐pyridazine derivatives 8 and 9 were obtained by reaction of 2 and 3 with malononitrile and ethyl cyanoacetate, respectively, and the isoxazolo‐pyridazines 11 by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium ethoxide solution. The intermediate 9 was separated by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium acetate solution.

📜 SIMILAR VOLUMES

POLYFUNCTIONALLY SUBSTITUTED HETEROCYCLE

POLYFUNCTIONALLY SUBSTITUTED HETEROCYCLES: SYNTHESIS OF NEW POLYFUNCTIONALLY SUBSTITUTED PHTHALAZINES, PYRIDO[3,4-C]PYRIDAZINES AND PYRAZOLO[3,4-C]PYRIDAZINES

✍ Erian, Ayman Wahba; Elkholy, Yehya Mahmoud; Al-arab, Elham Ezz; Elnagdf, Mohamed 📂 Article 📅 1997 🏛 Taylor and Francis Group 🌐 English ⚖ 349 KB

Synthesis of Novel Polyfunctionally Subs

Synthesis of Novel Polyfunctionally Substituted Thieno[2,3-c]pyridazines

✍ Gaber, Abd El-Aal M.; El-Gaby, Mohamed S. A.; El-Dean, Adel M. Kamal; Eyada, Has 📂 Article 📅 2004 🏛 Chinese Electronic Periodical Services 🌐 English ⚖ 62 KB

Polyfunctionally Substituted Heterocycle

Polyfunctionally Substituted Heterocycles: Synthesis of new polyfunctionally substituted phthalazines, thieno [3, 4-d] pyridazines and pyrido [3, 4-c] pyridazines

✍ Ahmed Hafez Hussein Elghandour; Abdel Haleem Mustafa Hussein; Prof. Dr. Mohamed 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB

Synthesis and antimicrobial activity of

Synthesis and antimicrobial activity of new polyfunctionally substituted pyridazines and their fused derivatives

✍ Elkholy, Yehya M. 📂 Article 📅 2005 🏛 Walter de Gruyter GmbH & Co. KG 🌐 English ⚖ 966 KB

Utility of [(p-Sulfonamidophenyl)azo]mal

Utility of [(p-Sulfonamidophenyl)azo]malononitrile in the Synthesis of Polyfunctionally Substituted Pyrimidine, Pyrazole, Isoxazole and Pyridazine Derivatives

✍ Hassanien, Abu Zeid Abd El-Baset; Saad Abdel Hafiz, Ibrahim; Elnagdi, Mohamed Hi 📂 Article 📅 1999 🏛 Science Reviews 2000 Ltd 🌐 English ⚖ 140 KB

ChemInform Abstract: A Convenient Synthe

ChemInform Abstract: A Convenient Synthesis of Polyfunctionally Substituted Benzo(b) thiophen-2-yl-pyrimidine, -pyrazole, -isoxazole, and -pyridazine Derivatives.

✍ S. M. SHERIF; R. M. MOHAREB; H. Z. SHAMS; H. M. M. GABER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB