Synthesis of polyazacyclophane-intercalator conjugates for combinatorial chemistry and RNA interaction studies

✍ Scribed by Tingmin Wang; Haoyun An; Becky D. Haly; P. Dan Cook

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2000
• Tongue: English
• Weight: 958 KB
• Volume: 37
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570370403

✦ Synopsis

Abstract

Anthraquinone and pyrene intercalators were conjugated to different positions of several polyaza‐pyridinocyclophanes by various linkers to provide thirteen new polyazacyclophane‐intercalator conjugates 1–13. These resulting conjugates contain two or three constrained secondary nitrogen atoms on the ring, which may serve as nucleophilic, coordinating or hydrogen‐bonding sites for combinatorial, RNA interaction and coordination studies.