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Synthesis of poly-substituted tetrahydropyridines from Baylis–Hillman adducts modified with N-allylamino group via radical cyclization

✍ Scribed by Hyun Seung Lee; Eun Sun Kim; Sung Hwan Kim; Jae Nyoung Kim

Book ID: 104096385
Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 401 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.02.225

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✦ Synopsis

An expedient method was developed for the synthesis of 1,4,5,6-tetrahydropyridines by radical cyclization protocol involving consecutive 1,5-hydrogen transfer and double bond isomerization process starting from Baylis-Hillman adducts.

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