✦ LIBER ✦

Synthesis of pinacol esters of 1-alkyl-1H-pyrazol-5-yl- and 1-alkyl-1H-pyrazol-4-ylboronic acids

✍ Scribed by Alexandre V. Ivachtchenko; Dmitry V. Kravchenko; Valentina I. Zheludeva; Dmitry G. Pershin

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 128 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410612

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Starting from 1__H__‐pyrazol, a wide number of 1‐alkyl‐1__H__‐pyrazol‐4‐yl and 1‐alkyl‐1__H__‐pyrazol‐5‐ylboronic acids and their pinacol esters were synthesized and characterized. The key step in the described methodology is the regioselective lithiation of the pyrazole ring. The synthesized pinacolates are stable under prolonged storage and can be used as convenient reagents in organic synthesis.

📜 SIMILAR VOLUMES

Synthesis of Pinacol Esters of 1-Alkyl-1

Synthesis of Pinacol Esters of 1-Alkyl-1H-pyrazol-5-yl- and 1-Alkyl-1H-pyrazol-4-ylboronic Acids.

✍ Alexandre V. Ivachtchenko; Dmitry V. Kravchenko; Valentina I. Zheludeva; Dmitry 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Carbon-13 NMR chemical shifts of 1-alkyl

Carbon-13 NMR chemical shifts of 1-alkyl-3(5)-cyano-1H-pyrazole-4-carboxylic acid esters

✍ George E. Babbitt; Michael P. Lynch; James R. Beck 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB

## Abstract A compilation of ^13^C NMR chemical shifts for 13 pairs of 3‐ and 5‐cyano‐substituted pyrazole regioisomers is reported. All of the ring carbon and cyano carbon ^13^C chemical shifts show a regular, predictable correlation with the particular isomer, whether 3‐cyano or 5‐cyano. These sh

Synthesis and Characterization of Some 2

Synthesis and Characterization of Some 2-(1-Phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)-4H-chromon-4-ones, 4-(2-Hydroxyphenyl)-6-(1-phenyl-3- (thiophen-2-yl)-1H-pyrazol-4-yl)pyrimidine-2-(1H)-thione, 2-(5-(1-Phenyl-3- (thiophen-2-yl)-1H-pyrazol-4-yl)-1H-pyrazol-3-yl)phenol and 2-(2,3-Dihydro-2-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)benzo[b] [1,4]thiazepin-4-yl)phenol.

✍ M. S. More; M. S. Shingare; S. B. Kale; N. R. Dalvi; B. K. Karale 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

ChemInform Abstract: Regiospecific Synth

ChemInform Abstract: Regiospecific Synthesis of 5-Trichloromethyl-1H-pyrazole and 1H-Pyrazole-5-carboxylic Ester Derivatives.

✍ Sidnei Moura; Alex F. C. Flores; Favero R. Paula; Ernani Pinto; Pablo Machado; M 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 47 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

New succinyl-spaced pyrazoles: Regiosele

New succinyl-spaced pyrazoles: Regioselective synthesis of 1,4-bis[5-(trichloromethyl)-1H-pyrazol-1-yl]butane-1,4-diones

✍ Helio G. Bonacorso; Cleber A. Cechinel; Gisele R. Paim; Marcos A. P. Martins; Ni 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 99 KB

The facile and convenient access by a conventional procedure in ethanol as solvent to a new series of succinyl-spaced pyrazoles including 1,4-bis[5-(trichloromethyl)-5-hydroxy-4,5-dihydro-1H-pyrazol-1yl]butane-1,4-diones (64-82%) and the respective dehydrated derivatives as 1,4-bis[5-(trichloromethy

Antimalarial Activity of 4-(5-Trifluorom

Antimalarial Activity of 4-(5-Trifluoromethyl-1H-pyrazol-1-yl)chloroquine Analogues.

✍ Wilson Cunico; Cleber A. Cechinel; Helio G. Bonacorso; Marcos A. P. Martins; Nil 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 18 KB 👁 2 views