Synthesis of Phosphorylated, Conjugation-Ready Di-, Tri- and Tetrasaccharide Fragments of the O-Specific Polysaccharide of V. cholerae O139.
✍ Scribed by Bart Ruttens; Rina Saksena; Pavol Kovac
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The title disaccharide, 2‐{2‐{2‐[(2‐ethoxy‐3,4‐dioxocyclobut‐1‐en‐1‐yl)amino]ethoxy}ethoxy}ethyl 2‐__O__‐(3,6‐dideoxy‐__α__‐L‐__xylo__‐hexopyranosyl)‐__β__‐d‐galactopyranoside cyclic 4,6‐(potassium phosphate) (**2**), was synthesized from the two isomeric linker‐equipped galactose accep
Methyl 4-(3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-2-O-methyl-alpha-D- mannopyranoside was acetylated, and the fully protected methyl glycoside was treated with dichloromethyl methyl ether-ZnCl2 (DCMME-ZnCl2) reagent to give 3-O-acetyl-4-(2,4-di-O-acetyl-3- deoxy-L-glycero-tetronamido)-4,6-dideoxy
Methyl O-(2,4-di-O-benzoyl-3-O-bromoacetyl-cY-~-rhamnopyranosyl)-(l + 3)-2,4-di-0-benzoyl--Lrhamnopyranoside was treated with dichloromethyl methyl ether and ZnCl, to give O-(2,4-di-O-benzoyl-3-0-bromoacetyl+L-rhamnopyranosylk(1 + 3)-2,4-di-O-benzoyl--L-rhamnopyranosyl chloride. Similar treatment of