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Synthesis of phosphonate derivatives of 2,3-dihydroindene

✍ Scribed by Monika Prokopowicz; Piotr Młynarz; Paweł Kafarski


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
235 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


Simple and convenient procedures for the synthesis of derivatives of 2,3-dihydroinden-2-ylphosphonic acid are developed. The reaction strategies utilize both functionalization of the already existing 2,3-dihydroindene skeleton and an annulation reaction starting from readily available o-disubstituted benzene derivatives.


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Phosphonic derivatives of carbohydrates:
✍ Giuseppe Guanti; Luca Banfi; Maria Teresa Zannetti 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 115 KB

A series of homologous racemic β-hydroxyaldehydes bearing a phosphonate group in the ω-position were synthesised and allowed to react with dihydroxyacetone phosphate (DHAP) via an enzymatic aldol addition catalysed by fructose 1,6-bisphosphate aldolase (FruA). After enzymatic dephosphorylation, a se