Synthesis of Phosphane Oxides and Phosphonates by Cerium-Mediated Addition of Organolithium Compounds to Chloro-Phosphorus Compounds
✍ Scribed by Renato Dalpozzo; Antonio De Nino; Daniela Miele; Antonio Tagarelli; Giuseppe Bartoli
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 122 KB
- Volume
- 1999
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
✦ Synopsis
The addition of organocerium reagents 2a-g to phosphinoyl benzyl group bound to the carbonyl moiety should be metallated. The latter reaction is the first reported synthesis chloride 1a or chlorophosphates 1b leads to the synthesis of phosphane oxides 3aa-ag and phosphonates 3bb, be in good of β-oxophosphane oxides by a simple reaction between enolates and a phosphorus(V) halide. to high yield. The reaction can be extended to cerium enolates 4 (of ketones) and 6 (of nitriles) except when a
The most common methods to prepare them [2c,6,7] are two-I-87030 Arcavacata di Rende (Cosenza), Italy