Synthesis of phidolopin, 7-(4-hydroxy-3-nitrobenzyl)-1,3-dimethylxanthine from the bryozoan phidolopora pacifica

✍ Scribed by Kosaku Hirota; Keiko Kubo; Yukio Kitade; Yoshifumi Maki

• Book ID: 104226957
• Publisher: Elsevier Science
• Year: 1985
• Tongue: French
• Weight: 121 KB
• Volume: 26
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)95097-4

✦ Synopsis

A total synthesis of a biologically active compound, phidolopin, was accomplished and its regioisomer was also synthesized.

Phidolopin (l), a new xanthine derivative recently isolated from a marine organism, the bryozoan Phidolopora pacifica, shows antifungal and antialgal