✦ LIBER ✦

Synthesis of Phenol and Quinone Metabolites of Benzo[a]pyrene, a Carcinogenic Component of Tobacco Smoke Implicated in Lung Cancer

✍ Scribed by Xu, Daiwang; Penning, Trevor M.; Blair, Ian A.; Harvey, Ronald G.

Book ID: 115485353
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 249 KB
Volume: 74
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo801864m

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 13C2-benzo[a]pyrene and its

Synthesis of 13C2-benzo[a]pyrene and its 7,8-dihydrodiol and 7,8-dione implicated as carcinogenic metabolites

✍ Chongzhao Ran; Daiwang Xu; Qing Dai; Trevor M. Penning; Ian A. Blair; Ronald G. 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 175 KB

Synthesis of the 13 C 2 -labelled analogues of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene and its active metabolites is described. The method entails Pd-catalyzed Suzuki-Miyaura coupling of a naphthalene boronic acid with 2-bromobenzene-1,3-dialdehyde followed by Wittig reaction

Synthesis of Suspected Carcinogenic Meta

Synthesis of Suspected Carcinogenic Metabolites of 7 H -Benzo[ c ]fluorene, a Coal Tar Component Implicated in Causation of Lung Tumors

✍ Wang, Ji-Quan; Weyand, Eric H.; Harvey, Ronald G. 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 76 KB

Induction of carbonyl reductase 1 (CBR1)

Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene

✍ James L. Kalabus; Qiuying Cheng; Raqeeb G. Jamil; Erin G. Schuetz; Javier G. Bla 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 756 KB

Carcinogen Metabolism in Human Lung Tiss

Carcinogen Metabolism in Human Lung Tissues and the Effect of Tobacco Smoking: Results from a Case-Control Multicenter Study on Lung Cancer Patients

✍ Helmut Bartsch, Stefano Petruzzelli, Silvio De Flora, Eino Hietanen, Anne-Marie 📂 Article 📅 1992 🏛 Environmental Health Information Service 🌐 English ⚖ 313 KB

Hypermethylation of RASSF1A and BLU tumo

Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: Implications for tobacco smoking during adolescence

✍ Carmen J. Marsit; Duk-Hwan Kim; Mei Liu; Philip W. Hinds; John K. Wiencke; Heath 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 82 KB 👁 1 views

## Abstract The putative tumor suppressors __RASSF1A__ and __BLU__ are mapped adjacent to one another on chromosome 3p21.3, a region frequently deleted in lung cancer. These genes are often inactivated by promoter hypermethylation, but the association of this inactivation with clinical features of