Synthesis of peptides employing Fmoc-ami
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Hosahydya N. Gopi; Vommina V. Suresh Babu
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Article
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1998
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Elsevier Science
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French
β 176 KB
Coupling of Frnoc-amino acid chlorides mediated by activated commercial zinc dust for the synthesis of peptides is described. The reaction is carried out in an organic medium. The necessity of using an inorganic base like NaHCO3/Na2CO3 or an organic base like DIEA/NMM/TEA/pyridine is circumvented. T