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Synthesis of peptides employing Fmoc-/Boc-/Z-amino acid fluorides and activated commercial zinc dust

✍ Scribed by Vommina V. Suresh Babu; Kuppanna Ananda


Publisher
Springer Netherlands
Year
2000
Tongue
English
Weight
354 KB
Volume
7
Category
Article
ISSN
1573-3149

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Synthesis of peptides employing Fmoc-ami
✍ Hosahydya N. Gopi; Vommina V. Suresh Babu πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 176 KB

Coupling of Frnoc-amino acid chlorides mediated by activated commercial zinc dust for the synthesis of peptides is described. The reaction is carried out in an organic medium. The necessity of using an inorganic base like NaHCO3/Na2CO3 or an organic base like DIEA/NMM/TEA/pyridine is circumvented. T