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Synthesis of p-fluorophenylflavazoles from dehydro-d-isoascorbic acid

✍ Scribed by El Sayed H. El Ashry; Mohamed Abdel Rahman; George H. Labib; Abdel Monem El-Massry; Ali Mofti

Book ID
108309074
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
250 KB
Volume
152
Category
Article
ISSN
0008-6215

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πŸ“œ SIMILAR VOLUMES

Total synthesis of lipoxins A4 and B4 fr
Total synthesis of lipoxins A4 and B4 from d-isoascorbic acid
✍ C. Gravier-Pelletier; J. Dumas; Y. Le Merrer; J.C. Depezay πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 French βš– 292 KB

A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure a-hydroxy and a$-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material. Connection by a six carbons unit uses Wittig-type reactions notably involving a stabilized arsonium yl