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Synthesis of oxazolo[3,2-b]hetero[1,2,4]thiadiazine S,S-dioxides

✍ Scribed by Salvador Vega; María Esther Arranz; Vicente J. Arán


Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
161 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis


Dedicated to Professor José Elguero on the occasion of his 70 th birthday

Six bromomethyl derivatives of the new 2,3-dihydrooxazolo [3,2-b] thieno[3,4-e][1,2,4]thiadiazine 5,5dioxides, 2,3-dihydrooxazolo[3,2-b]thieno[2,3-e][1,2,4]thiadiazine 5,5-dioxides and6,7-dihydrooxazolo-[3,2-b]pyrazolo[4,3-e][1,2,4]thiadiazine 9,9-dioxides heterocyclic ring systems were synthesized. These compounds are good intermediates for the preparation and development of promising antiviral and psychotropic drugs. The structures of the products are supported by different nmr spectroscopic methods and mass spectrometry.


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Synthesis of new hetero[1,2,4]thiadiazin
✍ Salvador Vega; María Esther Arranz; Vicente J. Arán 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 221 KB

## Abstract A series of 2‐substituted 2__H__‐thieno[3,4‐__e__][1,2,4]thiadiazin‐3(4__H__)‐one 1,1‐dioxides (**2**), 2‐substituted 2__H__‐thieno[2,3‐__e__][1,2,4]thiadiazin‐3(4__H__)‐one 1,1‐dioxides (**3**), 2‐substituted 4,6‐dihydropyrazolo[4,3‐__e__]‐[1,2,4]thiadiazin‐3(2__H__)‐one 1,1‐dioxides (