Synthesis of oxazolidines using DMSO/P4O10 as a formaldehyde equivalent
β Scribed by Jianmei Wang; Fernande D. Rochon; Yan Yang; Ling Hua; Margaret M. Kayser
- Book ID
- 108284211
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 288 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0957-4166
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The addition of 2-lithiobenzothiazole to D-gluconolactone followed by deoxygenation of the resulting ketose affords a mixture of benzothiazolyl aand b-D-glucopyranoside; treatment of this mixture with sodium methoxide gives the b-anomer from which the title aldehyde is obtained in a pure form by tra
A convenient and general one-pot, two-step protocol to prepare both N-acyl-1,3-thiazolidines and N-acyl-1,3-oxazolidines from formaldehyde, fatty acyl chlorides, and natural a-amino acids has been performed for the peculiar case of formaldehyde. In the presence of triethylamine to promote both the r