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Synthesis of orthogonally protected azalanthionines (lanazanines) by sequential ring-opening of N-substituted aziridine 2-carboxylates

✍ Scribed by O’Brien, Keith; ó Proinsias, Keith; Kelleher, Fintan


Book ID
120178124
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
447 KB
Volume
54
Category
Article
ISSN
0040-4039

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Synthesis of [4-11C]amino acids via ring
✍ N. M. Gillings; A. D. Gee 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 144 KB 👁 1 views

## Abstract Ring‐opening of __N__‐(__tert__‐butoxycarbonyl)aziridine‐2‐isopropyl carboxylate with no‐carrier‐added (n.c.a.) [^11^C]cyanide is reported. Following purification by HPLC, the protected D,L‐[4‐^11^C]__β__‐cyanoalanine was subsequently hydrolysed, to yield D,L‐[4‐^11^C]asparagine or D,L‐