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Synthesis of optically pure mechanism-based inhibitors of γ aminobutyric acid aminotransferase (GABA-T) via enzyme-catalyzed resolution

✍ Scribed by Alexey L Margolin


Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
259 KB
Volume
34
Category
Article
ISSN
0040-4039

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✦ Synopsis


Abstrack The kinetic resolution of ycthynyl-,y-allenyl-and y-vinyl GARA was accomplished by penicillin acylaaeaQlyxed hydrolysis of their N-pbcnylacctyl derivatives. The procedure employs inexpensive comme&lly svailable imnwbilixed enxym?..