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Synthesis of optically active α-methylamino acids and amides through biocatalytic kinetic resolution of amides

✍ Scribed by Mei-Xiang Wang; Jun Liu; De-Xian Wang; Qi-Yu Zheng


Book ID
108283971
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
185 KB
Volume
16
Category
Article
ISSN
0957-4166

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The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known