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Synthesis of optically active macrolides with hydrazide fragments from tetrahydropyran and L-(+)-tartaric acid derivatives

✍ Scribed by Ishmuratov, G. Yu.; Yakovleva, M. P.; Mingaleeva, G. R.; Shutova, M. A.; Muslukhov, R. R.; Vyrypaev, E. M.; Tolstikov, A. G.


Book ID
125358138
Publisher
Springer
Year
2013
Tongue
English
Weight
66 KB
Volume
49
Category
Article
ISSN
0009-3130

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## Abstract Epiclon [3a,4,5,7a‐tetrahydro‐7‐methyl‐5‐(tetrahydro‐2,5‐dioxo‐3‐furanyl)‐1,3‐isobenzofurandione] or [5‐(2,5‐dioxotetrahydrofurfuryl)‐3‐methyl‐3‐cyclohexyl‐1,2‐dicarboxylic acid anhydride] (1) was reacted with L‐isoleucine (2) in acetic acid and the resulting imide acid (3) was obtained