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Synthesis of Optically Active Amines Employing Recombinant ω-Transaminases in E. coli Cells

✍ Scribed by Dominik Koszelewski; Madeleine Göritzer; Dorina Clay; Birgit Seisser; Wolfgang Kroutil

Book ID
112018715
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
232 KB
Volume
2
Category
Article
ISSN
1867-3880

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## Abstract Various ω‐transaminases were tested for the synthesis of enantiomerically pure amines from the corresponding ketones employing D‐ or L‐alanine as amino donor and lactate dehydrogenase to remove the side‐product pyruvate to shift the unfavourable reaction equilibrium to the product side.

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