Synthesis of Optically Active 2,2-Difluorohomoallylalcohols by Lipase-Catalyzed Transesterification.
β Scribed by Masayuki Kirihara; Masashi Kawasaki; Hiroki Katsumata; Hiroko Kakuda; Motoo Shiro; Shigeki Kawabata
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 170 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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Kinetic resolution of 2-substituted 3-hydroxy esters was examined by lipase PS catalyzed transesterification using vinyl acetate as an acyl donor. Resolution of (Β±)-syn-and -anti-1a, -1e possessing a small methyl group at the C-3 position was accomplished enantioselectively. The outcome of the resol
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