Synthesis of Optically Active 2- and 3- Indolylglycine Derivatives and their Oxygen Analogues
โ Scribed by Goswami, Koushik; Duttagupta, Indranil; Sinha, Surajit
- Book ID
- 118019255
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 458 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
1R,5S)-2,8-Dioxabicyclo[3.3.0]octan-3-one and its derivatives, important subunits in various biologically active natural products, have been synthesized based on a new approach using the asymmetric oxyselenenylation of 2,3-dihydrofuran as the key step.
A variety of optically active 3-substituted cis-cyclohexane-3,5-dien-1,2-diol acetonides were readily prepared from chiral 5-(tert-butyldimethylsilyloxy)-2-cyclohexenone through a seven-step reaction in good overall yield. The synthesis also allowed preparation of the acetonide having an 2 H-atom at