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Synthesis of oligonucleotides with glucosamine at the 3′-position and evaluation of their biological activity

✍ Scribed by Luo, Xiong; Sugiura, Takahiro; Nakashima, Remi; Kitamura, Yoshiaki; Kitade, Yukio


Book ID
121719029
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
726 KB
Volume
23
Category
Article
ISSN
0960-894X

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AbstractÐAmong the hapalosin derivatives synthesized, the compounds carrying methyl (5a), methylthioethyl (5d) and phenylmethyl (5e) groups at the C12 position possess only the cis-peptide structure, in contrast to the cases of 5b and 5c. In addition to their conformational stability, the biological