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Synthesis of Oligonucleotides on a Polymeric Carrier

✍ Scribed by Prof. Dr. F. Cramer; Dipl.-Chem. H. Köster


Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
211 KB
Volume
7
Category
Article
ISSN
0044-8249

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📜 SIMILAR VOLUMES


Oligonucleotide Synthesis on a Polymeric
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Various methoda for the ryntherir of oligonucleotidee on polymeric carriers are in progreea in thim laboratory. We first used makroporous, nonswellable polystyrene 1, 3. 5) and were able to synthesize dT(pdT), and dTpdTpdApdCpdCpdTpdA 4,6) . In another study we used popcorn polyetyrene for the synth

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We wish to report the convenient stepwise synthesis of the pentanucleotide d-TpTpTpTpT, using commercially available crosslinked polyacrylmorpholide as an insoluble support. The conversion in each step ranged between 84 and 90% based