Asymmetric synthesis of α-amino acid der
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Nan Zheng; Joseph D. Armstrong III; J.Christopher McWilliams; R.P. Volante
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Article
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1997
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Elsevier Science
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French
⚖ 218 KB
The utility of lithium t-butyl-N-tosyloxycarbamate (LiBTOC) as a ( + )NHBOC synthon in highly diastereoselective reactions with chiral cis-aminoindanol derived amide cuprates is described. The diastereoselectivities of these reactions ranged from 96% to greater than 99%. The subsequent transformatio