The preparation of a beta-galactosylated hydroxyproline derivative and its use in the multi-gram solid-phase synthesis of the potent analgesic neoglycopeptide O1.5-beta-D-galactopyranosyl [D-Met2, Hyp5]enkephalinamide is described in this paper. The most closely related impurities have been identifi
✦ LIBER ✦
Synthesis of Nα-[3H]Acetyl-L-lysine Chloromethyl Ketone and Its Use in the Fluorographic Detection of Proteases
✍ Scribed by M. Nishikata
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 435 KB
- Volume
- 214
- Category
- Article
- ISSN
- 0003-2697
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## Abstract Sumitriptan (1), a non‐selective 5‐HT~1B/1D~ agonist is an effective therapeutic agent for the acute treatment of migraine, but it is contraindicated for use in patients with known heart disease. The first Selective Serotonin One F Receptor Agonist (SSOFRA), 5‐(4′‐fluorobenz‐amido)‐3‐(_