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Synthesis of Novel Retinoid X Receptor-Selective Retinoids

✍ Scribed by Faul, Margaret M.; Ratz, Andrew M.; Sullivan, Kevin A.; Trankle, William G.; Winneroski, Leonard L.

Book ID: 111926675
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 148 KB
Volume: 66
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo0103064

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Retinoids mediate a number of physiological pathways through their effects on cellular growth and differentiation. Upon binding to retinoic acid receptors (RARs) and retinoid X receptors (RXRs), retinoids regulate cellular processes by directly modulating the expression of responsive genes. The wide