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Synthesis of Novel (Phenylalkyl)amines for the Investigation of StructureActivity Relationships, Part 3 : 4-Ethynyl-2,5-dimethoxyphenethylamine (=4-Ethynyl-2,5-dimethoxybenzeneethanamine; 2C-YN)

✍ Scribed by Trachsel, Daniel (author)


Book ID
102255222
Publisher
Verlag Helvetica Chimica Acta AG
Year
2003
Tongue
German
Weight
81 KB
Volume
86
Category
Article
ISSN
0018-019X

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Synthesis of Novel (Phenylalkyl)amines f
✍ Trachsel, Daniel (author) 📂 Article 📅 2003 🏛 Verlag Helvetica Chimica Acta AG 🌐 German ⚖ 81 KB

## Abstract An easy and efficient pathway for the preparation of 4‐ethynyl‐2,5‐dimethoxyphenethylamine (=4‐ethynyl‐2,5‐dimethoxybenzeneethanamine; 2C‐YN; **1**) was developed, an ethynyl analogue of the potent 5‐HT~2A/C~ agonists, __e.g.__, 4‐iodo‐2,5‐dimethoxy‐amphetamine (DOI; **2b**). The ethyny