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Synthesis of novel mono-substituted polyacetylenes bearing functional urea groups in side chains

✍ Scribed by Jianping Deng; Weiguo Zhao; Wantai Yang


Book ID
108257426
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
260 KB
Volume
67
Category
Article
ISSN
1381-5148

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Facile production of mono-substituted ur
✍ Maria L. Diss; Alan J. Kennan πŸ“‚ Article πŸ“… 2007 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 193 KB πŸ‘ 1 views

## Abstract A method is reported for the straightforward generation of urea‐containing peptides during Boc solid phase peptide synthesis. Primary amine side chains are converted to mono‐alkyl ureas in two steps via an intermediate __p__‐nitrophenyl carbamate. Use of __p__‐methoxybenzyl amine as an