Facile production of mono-substituted ur
β
Maria L. Diss; Alan J. Kennan
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Article
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2007
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Wiley (John Wiley & Sons)
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English
β 193 KB
π 1 views
## Abstract A method is reported for the straightforward generation of ureaβcontaining peptides during Boc solid phase peptide synthesis. Primary amine side chains are converted to monoβalkyl ureas in two steps via an intermediate __p__βnitrophenyl carbamate. Use of __p__βmethoxybenzyl amine as an