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Synthesis of novel disaccharides based on glycosyltransferases: β1,4galactosyltransferase

✍ Scribed by Chi-Huey Wong; Thomas Krach; Christine Gautheron-Le Narvor; Yoshitaka Ichikawa; Gary C. Look; Federico Gaeta; David Thompson; K.C. Nicolaou

Book ID: 104225858
Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 205 KB
Volume: 32
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)93482-8

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✦ Synopsis

pl,4Galactosyltransferase and p-galactosidase have been investigated with regard to their acceptor specificity and used in the synthesis of galactosides using Qhioglucose, deoxyazaglucose, glucal, modified N-acetylglucosamine and glucose derivatives as acceptors.

Sophisticated chemical procedures for protection/deprotection, activation, and coupling are now

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