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Synthesis of novel bicyclic nitrogen heterocycles by the intramolecular dipolar cycloaddition reaction of nitrones with allenes and alkynes

✍ Scribed by Albert Padwa; Michael Meske; Zhijie Ni


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
912 KB
Volume
51
Category
Article
ISSN
0040-4020

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## Abstract magnified image Asymmetric 1,3‐dipolar cycloadditions of chiral nitrones to 1‐propene‐1,3‐sultone (**1**) were investigated. Chiral nitrones **6a‐e** reacted with sultone **1** in toluene at 90 Β°C for 24‐36 h to give the corresponding isoxazolidines in moderate yields with high regiose