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Synthesis of novel aza analogues of 2-substituted-2,3-dihydro-1,4-benzodioxins as potential new scaffolds for drug discovery

✍ Scribed by Encarna Matesanz; Jesús Alcázar; J.Ignacio Andrés; Jose M. Bartolomé; Marcel De Bruyn; Javier Fernández; Kristof Van Emelen

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 221 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)00281-8

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✦ Synopsis

New synthesis approaches that have led to a series of novel aza analogues of the 2-substituted-2,3-dihydro-1,4-benzodioxin core, bearing versatile bromomethyl group on the non aromatic oxygenated ring, are described. According to their structures these novel scaffolds can be useful intermediates for the preparation of potential new therapeutic agents.

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