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Synthesis of novel amino acids, l-bis-tetrahydrofuranylglycines

✍ Scribed by Ei'ichi Ami; S Rajesh; Jung Wang; Tooru Kimura; Yoshio Hayashi; Yoshiaki Kiso; Toshimasa Ishida

Book ID: 104250871
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 138 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)00448-3

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✦ Synopsis

Novel amino acids, enantiomerically pure L-bis-tetrahydrofuranylglycines, were efficiently synthesized from dihydrofuran utilizing radical cyclization and chiral azidation as the key steps. The absolute stereochemistry of both diastereomers has been ascertained by their crystal structures.

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