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Synthesis of novel 4-(1-ethoxycarbonyl-methylidene)-azetidin-2-ones via a Lewis acid-catalyzed reaction of ethyl diazoacetate

โœ Scribed by Gianfranco Cainelli; Paola Galletti; Massimo Gazzano; Daria Giacomini; Arianna Quintavalla


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
127 KB
Volume
43
Category
Article
ISSN
0040-4039

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Ethyl diazoacetate reacts with a variety of aldehydes in the presence of a Lewis acid catalyst to give either [~-keto esters or a-formyl esters, the types of products mainly depending upon the nature of Lewis acid catalysts employed. Reactions catalyzed by Lewis acids such as SnCI2 and SnCl4 provide