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Synthesis of Novel 2,5-Disubstituted 1,3,4-Thiadiazoles for Their Potential Anticonvulsant Activity: Pharmacophoric Model Studies

✍ Scribed by Harish Rajak; Ravitas Deshmukh; Navneet Aggarwal; Sushil Kashaw; Murli Dhar Kharya; Pradeep Mishra


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
484 KB
Volume
342
Category
Article
ISSN
0365-6233

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Studies on Synthesis and Pharmacological
✍ Vinod Mathew; Devasahayam Giles; Jathi Keshavayya; Vijaya P. Vaidya 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 475 KB

## Abstract 4‐Amino‐5‐substituted aryl‐3‐mercapto‐1,2,4‐triazoles are versatile synthons for constructing various biologically active heterocycles. Starting from 4‐amino‐5‐substituted aryl‐3‐mercapto‐1,2,4‐triazole **3a**–**c**, a series of new 3,5‐disubstituted‐1,2,4‐triazolo‐[3,4‐__b__]1,3,4‐thia