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Synthesis of nonproteinogenic amino acids part 3: conversion of glutamic acid into γ,δ-unsaturated α-amino acids

✍ Scribed by Jack E. Baldwin; Michael North; Anthony Flinn; Mark G. Moloney


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
837 KB
Volume
45
Category
Article
ISSN
0040-4020

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Non-proteinogenic amino acid synthesis:
✍ Jack E Baldwin; Mark G Moloney; Michael North 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 609 KB

A general, stereospecific, synthesis of S,Y-unsaturated a-amino acids using the S-anion derived from aspartic acid is described . S,Y-Unsaturated amino acids have been found to be reversible or irreversible inhibitors of a number of enzymes,' and this has prompted a number of racemic syntheses of th