✦ LIBER ✦
Synthesis of non-steroidal antiinflammatory drug analogues for selective studies on the COX-II enzyme
✍ Scribed by Steven A. Fleming; Michael D. Ridges; Anton W. Jensen
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 294 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Synthesis of the azido substituted non-steroidal antiinflammatory drug 2-(2,6-dichloroanilino)phenylacetic acid and isotope labeling of this compound have been perfoxmed and are described. Initial evaluation of the binding ability and photoreactivity indicates that this compound has potential for photoaffinity labeling as well as enzyme selectivity studies.