A Chemical Synthesis of Nicotinamide Adenine Dinucleotide (NAD + ). -Via a practical synthesis of Ξ²-nicotinamide mononucleotide (IV) and an efficient novel catalyzed pyrophosphate formation as the key step the title compound(VI) is synthesized. -(LEE, JAEMOON; CHURCHIL, HYWYN;
Synthesis of Nicotinamide Adenine Dinucleotide (NAD) Analogues with a Sugar Modified Nicotinamide Moiety
β Scribed by Natasha Goulioukina; Johny Wehbe; Damien Marchand; Roger Busson; Eveline Lescrinier; Dieter Heindl; Piet Herdewijn
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- German
- Weight
- 255 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0018-019X
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β¦ Synopsis
Abstract
The synthesis of nicotinamide adenine dinucleotide (NAD) analogues in which the ribose unit of the nicotinamide moiety is replaced by a hexitol, altritol, and cyclohexenyl sugar mimic is described.
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