Synthesis of New β-Hydroxy Nitrate Esters as Potential Glycomimetics or Vasodilators

Synthesis of α,α-Difluoro-β-amino Esters

Synthesis of α,α-Difluoro-β-amino Esters or gem-Difluoro-β-lactams as Potential Metallocarboxypeptidase Inhibitors

✍ Nicolas Boyer; Philippe Gloanec; Guillaume De Nanteuil; Philippe Jubault; Jean-C 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

## Abstract The synthesis of __gem__‐difluorinated β‐lactams and __gem__‐difluorinated β‐amino acids, each possessing a potential basic functional group, from ethyl bromodifluoroacetate and either imines (for β‐lactams) or __N__‐(α‐aminoalkyl)benzotriazoles (for β‐amino esters) was investigated. A