## Abstract Syntheses of some new thiosemicarbazides, thiadiazoles, triazoles and their derivatives are described. Most of the compounds were screened for activity against ranikhet disease virus (RDV) in a stationary culture of chorioallantoic membranes of chick embryo. Some of them exhibited signi
β¦ LIBER β¦
Synthesis of New Substituted Thiosemicarbazides and Their Cyclization to Triazole- and Thiadiazole Derivatives.
β Scribed by Ioana Saramet; Constantin Draghici; Corina Barcutean; Valeria Radulescu; Teodora Loloiu; Mircea D. Banciu
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 16 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
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## Abstract Reaction of 4βphenylβ4__H__β1,2,4βtriazoleβ3βthione with ethyl bromoacetate has led to the formation of ethyl [(4βphenylβ4__H__β1,2,4βtriazolβ3βyl)sulfanyl]acetate **1**, the structure of which was confirmed by Xβray analysis. In the next reaction with 80% hydrazide hydrate, appropriate